Invasive pulmonary aspergillosis associated with viral pneumonitis

The occurrence of invasive pulmonary aspergillosis (IPA) in critically ill patients with viral pneumonitis has increasingly been reported recent years. Influenza-associated (IAPA) and COVID-19-associated (CAPA) are the two most common forms this fungal infection. These diseases cause high mortality patients, whom were previously immunocompetent. pathogenesis IAPA CAPA is still not fully understood, but involves viral, host factors. In article, we discuss several aspects regarding CAPA, including their possible pathogenesis, use immunotherapy, future challenges.